The pedigree below shows a man affected with dominantly inherited Huntington disease (a rare, autosomal disorder). Both of his children have elected pre-natal diagnosis, although they do not wish their status to be evaluated. The Southern blot below has been typed for an RFLP with 2 morphs: 4.9kb fragment or 3.7kb and 1.2kb fragments. The restriction fragment locus is 4 map units away from the Huntington locus. Calculate the chance that both fetuses will inherit the allele for Huntington. (Assume the affected man is not homozygous for the rare Huntington allele.)
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The pedigree below shows a man affected with dominantly inherited Huntington disease (a rare, autosomal disorder). was first posted on October 9, 2020 at 7:46 am.
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The pedigree below shows a man affected with dominantly inherited Huntington disease (a rare, autosomal disorder). was first posted on October 9, 2020 at 7:56 am.
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